DRIED VACCINE

The Present Position of Freeze-Dried BCG Vaccine

I reviewed in 1952 the literature on freeze-dried BCG vaccine in order to help evaluate the relative merits of fresh liquid and dried vaccines on the basis of the results of vaccination. More BCG production centres have since taken to the preparation of dried BCG vaccine for either experimental use or for vaccination. In India, the scene of activity of the mass vaccination campaign has shifted ...

Determination of the Viability at +4°C of Freeze-Dried Attenuated Live Agalactiae Vaccine

Stability of Freeze-dried Inactivated Japanese Encephalitis Vaccine under Different Experimental Conditions

Stability of three batches of freeze dried inactivated mouse brain Japanese encephalitis vaccine, was evaluated in terms of percentage drop or otherwise in potency from their respective initial titers, after exposure to different experimental conditions for 4 -12 weeks. The potency was assayed by plaque reduction neutralization assay (PRNT) using chick embryo fibroblasts cells. The vaccine has ...

Development of liposome-based freeze-dried rods for vaginal vaccine delivery against HIV-1.

summary The present investigation deals with development and characterization of the liposomes-based freeze-dried rods for the vaginal delivery of gp140 antigen in mice. Positively charged, negatively charged and neutral liposomes were prepared and characterized for various parameters e.g. morphology, size, polydispersity index, zeta potential and antigen encapsulation efficiency. To further im...

Preparation and properties of a freeze-dried B.C.G. vaccine of increased stability.

A stable B.C.G. vaccine, prepared and distributed in the freeze-dried form, is now accepted for use in many parts of the world. Recent trials (Medical Research Council, 1958, 1960; Griffiths and Gaisford, 1956) have confirmed that the freeze-dried vaccine induces a high degree of tuberculin sensitivity without untoward local reactions. From its stability the freeze-dried vaccine has undoubted a...